Pachydermodactyly is a rare and benign disease that may be idiopathic, genetic, acquired as a response to repetitive trauma, or associated with several other acquired conditions often pushing the health caregiver to do a bunch of costly lab tests and diagnostic workups to rule out other entities.All health care givers must be aware about this disea
Abstract Induced oncoproteins degradation provides an attractive anti-cancer modality.Activation of anaphase-promoting complex (APC/CCDH1) prevents cell-cycle entry by targeting Foam Earpads crucial mitotic proteins for degradation.Phosphorylation of its co-activator CDH1 modulates the E3 ligase activity, but little is known about its regulation af
We study the quantum and classical Miscellaneous Skate evolution of a system of three harmonic modes interacting via a trilinear Hamiltonian.With the modes prepared in thermal states of different temperatures, this model describes the working principle of an absorption refrigerator that transfers energy from a cold to a hot environment at the expen
The solute copyright (SLC) Ball - Elastic Goods - Sliding Short superfamily represents the biggest family of transporters with important roles in health and disease.Despite being attractive and druggable targets, the majority of SLCs remains understudied.One major hurdle in research on SLCs is the lack of tools, such as cell-based assays to investi